Gareth J Sanger Selected Research

Emetics

1/2023	Review article: An analysis of the pharmacological rationale for selecting drugs to inhibit vomiting or increase gastric emptying during treatment of gastroparesis.
1/2022	Anti-emetic effects of thalidomide: Evidence, mechanism of action, and future directions.
3/2021	COVID-19, nausea, and vomiting.
1/2014	Nausea and the quest for the perfect anti-emetic.
1/2013	Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors.
1/2007	Differential effects of dexamethasone, ondansetron and a tachykinin NK1 receptor antagonist (GR205171) on cisplatin-induced changes in behaviour, food intake, pica and gastric function in rats.
10/2006	Treatment of nausea and vomiting: gaps in our knowledge.
1/2006	Anti-emetic activity of ghrelin in ferrets exposed to the cytotoxic anti-cancer agent cisplatin.
6/2005	Pica--a model of nausea? Species differences in response to cisplatin.

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Gareth J Sanger Research Topics

Disease

20	Nausea 12/2023 - 03/2005
16	Vomiting 12/2023 - 03/2005
8	Gastroparesis 01/2023 - 01/2007
7	Neoplasms (Cancer) 01/2022 - 01/2006
4	Constipation 01/2017 - 05/2008
4	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2016 - 10/2006
3	Inflammation (Inflammations) 01/2022 - 01/2021
3	Pica (Geophagia) 01/2014 - 06/2005
3	Dyspepsia (Indigestion) 09/2008 - 10/2006
2	Muscle Hypertonia 12/2022 - 01/2022
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 09/2008 - 04/2004
2	Hypersensitivity (Allergy) 10/2006 - 04/2004
1	Tardive Dyskinesia 01/2023
1	Confusion (Bewilderment) 01/2023
1	Drug-Related Side Effects and Adverse Reactions 01/2023
1	Obesity 01/2022
1	COVID-19 03/2021
1	Anorexia 03/2021
1	Celiac Disease (Celiac Sprue) 01/2021
1	Growth Disorders 01/2021
1	Sleep Initiation and Maintenance Disorders (Insomnia) 11/2020
1	Respiratory Insufficiency (Respiratory Failure) 11/2020
1	Opioid-Related Disorders (Opiate Addiction) 11/2020
1	Malaria 01/2018
1	Motion Sickness (Airsickness) 01/2018
1	Urticaria (Hives) 01/2018
1	Prader-Willi Syndrome (Syndrome, Prader-Willi) 01/2017
1	Digestive System Diseases 01/2017
1	Ileus 01/2016
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2016

Drug/Important Bio-Agent (IBA)

10	AntiemeticsIBA 12/2023 - 03/2005
9	EmeticsIBA 01/2023 - 06/2005
7	GhrelinIBA 01/2017 - 01/2006
6	MotilinIBA 01/2023 - 07/2011
5	Ghrelin ReceptorsIBA 03/2017 - 03/2008
4	Vasopressins (Vasopressin)IBA 09/2023 - 01/2014
4	Metoclopramide (Reglan)FDA LinkGeneric 01/2023 - 09/2013
4	motilin receptorIBA 01/2017 - 01/2013
4	Cisplatin (Platino)FDA LinkGeneric 01/2007 - 03/2005
3	Erythromycin (Erycette)FDA LinkGeneric 01/2023 - 01/2013
3	Atropine FDA LinkGeneric 05/2020 - 09/2013
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2014
3	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 01/2018 - 03/2005
2	Dopamine AntagonistsIBA 01/2023 - 01/2018
2	Hypnotics and Sedatives (Sedatives)IBA 01/2022 - 01/2018
2	Opioid Analgesics (Opioids)IBA 11/2020 - 10/2006
2	Analgesics (Analgesic Drugs)IBA 01/2018 - 04/2004
2	N- (3- fluorophenyl)- 1- ((4- (((3S)- 3- methyl- 1- piperazinyl)methyl)phenyl)acetyl)- 4- piperidinamineIBA 01/2016 - 01/2016
2	Hormones (Hormone)IBA 01/2013 - 03/2008
2	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2013 - 07/2007
2	Peptides (Polypeptides)IBA 01/2010 - 03/2008
2	Ondansetron (Zofran)FDA LinkGeneric 01/2007 - 03/2005
2	TachykininsIBA 01/2007 - 04/2004
2	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 10/2006 - 03/2005
2	Neurokinin-3 ReceptorsIBA 10/2006 - 03/2005
1	Muscarinic AntagonistsIBA 01/2023
1	Mirtazapine (Rexer)FDA LinkGeneric 01/2023
1	Amitriptyline (Elavil)FDA LinkGeneric 01/2023
1	Nortriptyline (Aventyl)FDA LinkGeneric 01/2023
1	Therapeutic UsesIBA 01/2023
1	Serotonin 5-HT4 Receptor AgonistsIBA 01/2023
1	Serotonin 5-HT3 Receptor AntagonistsIBA 01/2023
1	Epinephrine (Adrenaline)FDA LinkGeneric 12/2022
1	Arginine Vasopressin (Argipressin)IBA 12/2022
1	Glutamic Acid (Glutamate)FDA Link 01/2022
1	RyanodineIBA 01/2022
1	ProstaglandinsIBA 01/2022
1	LipidsIBA 01/2022
1	Growth Differentiation Factor 15IBA 01/2022
1	Thalidomide (Thalomid)FDA Link 01/2022
1	Angiotensin IIIBA 03/2021
1	VaccinesIBA 01/2021
1	Tight Junction ProteinsIBA 01/2021
1	Olanzapine (Zyprexa)FDA Link 11/2020
1	BenzodiazepinesIBA 11/2020
1	Tetrodotoxin (Tetradotoxin)IBA 05/2020
1	Krebs-Ringer solutionIBA 05/2020
1	Substance PIBA 01/2018
1	Histamine H1 AntagonistsIBA 01/2018
1	Dimenhydrinate (DMH)FDA LinkGeneric 01/2018
1	Domperidone (Domperidon)IBA 01/2018
1	Dopamine D2 Receptor AntagonistsIBA 01/2018
1	Chlorpromazine (Thorazine)FDA Link 01/2018
1	PhenothiazinesIBA 01/2018
1	Plant ExtractsIBA 01/2018
1	Quinine (Quinson)FDA Link 01/2018
1	Dopamine Receptors (Dopamine Receptor)IBA 01/2018
1	Histamine Receptors (Histamine Receptor)IBA 01/2018
1	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2018
1	Scopolamine (Hyoscine)FDA Link 01/2018
1	Granisetron (Kytril)FDA LinkGeneric 01/2018
1	Investigational DrugsIBA 03/2017
1	relamorelinIBA 01/2016
1	PhysostigmineIBA 09/2013
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2013
1	Nicotine FDA Link 01/2013

Therapy/Procedure

6	Drug Therapy (Chemotherapy) 12/2023 - 01/2007
2	Palliative Care (Palliative Therapy) 11/2020 - 01/2018
2	Therapeutics 01/2019 - 03/2017
1	Baths 05/2020